Hematology Oncology

Allogeneic Bone Marrow Transplantation From A Related Donor

The process of taking stem cells from the “bone marrow” or “environmental blood (blood in their veins)” from the patient’s sibling, relatives, or non-relatives and transferring them to the patient is called allogeneic stem cell transplantation. In this article, we will look at the details together.

What is Allogeneic Bone Marrow Transplantation?

If the stem cells are obtained from the bone marrow, it is called “bone marrow” transplantation, if it is obtained from circulating blood, “environmental blood stem cell transplantation”, if it is obtained from the umbilical cord of a newborn baby, it is called “cord blood stem cell transplantation”.

If a patient is looking for a donor for allogeneic stem cell transplantation, the tissue group of his/her siblings, if any, is checked first. If a fully compatible donor is not found among the siblings, the patient’s close relatives can be screened, and if there is no positive result, “bone marrow banks” are applied. The time taken to search for suitable donors from bone marrow banks can take between 2 and 10 months.

Before Allogeneic Bone Marrow Transplantation

In allogeneic stem cell transplantation, as in autologous stem cell transplantation, high-dose chemotherapy is applied to the patient first. Then, stem cells collected from a healthy donor (sibling, relative or unrelated person) are transplanted to the patient. These stem cells enable the production of healthy blood cells in the patient’s bone marrow.

Who is Suitable for Allogeneic Bone Marrow Transplantation?

Although allogeneic stem cell transplantation is mostly applied in cancer patients, it can also be preferred in the treatment of diseases that cause bone marrow failure. The main diseases in which allogeneic stem cell transplantation can be applied can be listed as follows:

Acute leukemias
Myelodysplastic syndrome
Severe aplastic anemia and other bone marrow failure conditions
Non-Hodgkin lymphoma
Hodgkin lymphoma
Chronic leukemias

Fibo Health provides quality treatment options in Turkey to the patients who are coming from all around the world. Istanbul is one of the most populous cities in the world. There are many hospitals and clinics that provide world-class care for their patients. Fibo Health’s team searches for the best doctors and hospitals, so we make sure to bring you to the most experienced health care professionals in Turkey.